Discussions

The LPS-induced sepsis mouse model is a widely used experimental system for studying sepsis and its underlying mechanisms. This model, which involves the administration of lipopolysaccharide (LPS) to mice, mimics the inflammatory response seen in human sepsis. Researchers use this model to explore various aspects of sepsis, including immune dysregulation, organ failure, and the development of effective treatments. By examining the pathophysiology of LPS-induced sepsis, scientists can identify potential therapeutic targets and evaluate new drug candidates aimed at mitigating the effects of sepsis in clinical settings.